Synthetic Biology

Synthetic Biology

Glieder, Anton; Kubicek, Christian P.; Mattanovich, Diethard; Wiltschi, Birgit; Sauer, Michael

Springer International Publishing AG

08/2016

368

Mole

Inglês

9783319355153

15 a 20 dias

This book provides a comprehensive, up-to-date overview of the opportunities and challenges of the complex field of synthetic biology, which combines various scientific disciplines.
Xenobiotic life (artificial cells and cell like structures, biological nanostructures, XNA).- Novel DNA and RNA (synthetic promoters, riboswitches, small RNAs, ribozymes, adaptamers, DNA walker, DNA machines).- Expansion of the genetic code and protein building blocks (orthogonal mRNA-ribosome pairs, non canonical amino acids).- DNA logics and circuit design (including sensors, TALORs, genome rewiring repressilator, oscillator, metabolator, "Multicellular circuits").- Protein engineering (directed evolution, domain engineering).- Synthetic metabolic pathways (engineered pathways, non natural pathways, scaffolding).- Reengineered chassis cells (minimal organisms, platform hosts, minimal genomes, synthetic genomes).- In silico simulation and design of complex metabolic and signalling networks.- Novel synthetic biomaterials.- Key methods for synthetic biology (assembly technologies, genome engineering technologies, DNA synthesis, Standardization).- Public awareness and risk management.
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